Journal of the American College of Cardiology – Mechanisms Contributing to the Progression of Ischemic and Nonischemic Dilated Cardiomyopathy

by stemedica admin | Nov 3, 2015 | Publications

Abstract Over the past 1.5 decades, numerous stem cell trials have been performed in patients with cardiovascular disease. Although encouraging outcome signals have been reported, these have been small, leading to uncertainty as to whether they will translate into...

Journal of Cardiovascular Medicine – Rationale and design of a randomized controlled trial of allogeneic mesenchymal stem cells in patients with nonischemic cardiomyopathy

by user | Oct 13, 2015 | Publications

Abstract Aims: This article describes an ongoing study investigating the safety and efficacy of ischemia-tolerant mesenchymal stem cell (MSC) therapy in patients with nonischemic heart failure and dysfunctional viable myocardium without scarring. This study will...

Journal of the American College of Cardiology – Mechanisms Contributing to the Progression of Ischemic and Nonischemic Dilated Cardiomyopathy

by user | Sep 1, 2015 | Publications

Possible Modulating Effects of Paracrine Activities of Stem Cells Abstract Over the past 1.5 decades, numerous stem cell trials have been performed in patients with cardiovascular disease. Although encouraging outcome signals have been reported, these have been small,...

Combined Transplantation of Human Neuronal and Mesenchymal Stem Cells following Spinal Cord Injury

by stemedica admin | Mar 2, 2013 | Publications

Abstract Transplantation of human fetal neural stem cells (hNSCs) previously demonstrated significant functional recovery after spinal cord contusion in rats. Other studies indicated that human mesenchymal stem cells (hMSCs) can home to areas of damage and cross the...

Journal of Neurosurgery – Chicken embryonic brain: an in vivo model for verifying neural stem cell potency

by user | Mar 1, 2013 | Publications

Abstract Object. The multipotency of neural stem cells (NSCs) can be assessed in vitro by detection of stage-specific markers in response to a suitable differentiation signal. This test is frequently used because it is fast and affordable. However, it is not clear how...

Stem Cell Research & Therapy- High targeted migration of human mesenchymal stem cells grown in hypoxia is associated with enhanced activation of RhoA

by user | Jan 7, 2013 | Publications

Abstract Introduction A feature which makes stem cells promising candidates for cell therapy is their ability to migrate effectively into damaged or diseased tissues. Recent reports demonstrated the increased motility of human mesenchymal stem cells (hMSC) grown under...